Endocrine Abstracts

Background and aims: It is reported that intracellular adhesion molecule-1 (ICAM-1) is important in autoimmune thyroid diseases also it is an important point that ICAM-1 level is high in postoperative hypothyroid cases. In literature, it is said that the level of plasma soluble ICAM-1 can be used as a evidence immune system activation and inflammation, and also it can be used for the diagnosis of some inflammatory and autoimmune diseases. The aim of our was to compare the leve...

Introduction: We evaluated the characteristics of differentiated thyroid carcinoma in geriatric patients and factors that influenced long-term survival in this retrospective study design. Among 1188 patients with differentiated thyroid carcinoma who were treated at our institution over the past 7 years, 144 patients were identified who were age 65 years or older(age range:65–88 years) at the time of their initial diagnosis. This study conducted a retrospective analysis of...

Introduction: The term congenital adrenal hyperplasia (CAH) encompasses a group of autosomal recessive disorders, each of which involves a deficiency of an enzyme involved in the synthesis of cortisol, aldosterone, or both. Deficiency of 21-hydroxylase, resulting from mutations or deletions of CYP21A, is the most common form of CAH, accounting for more than 90% of cases.Case report: Two female siblings were referred to endocrine clinic with the complain ...

Background: Our aim was to investigate levels of lipocalin-2 and its relationship with metabolic factors in women with polycystic ovary syndrome (PCOS).Materials/subjects and methods: In this cross-sectional study, two groups of women were studied: group 1 consisted of women with PCOS (n=30), and group 2 consisted of control women with normal ovulatory function (n=30). The circulating levels of lipocalin were measured.<p class="abstext"...

Introduction: Carbohydrate antigen 19-9 (CA 19-9) is a glycosphingolipid of the Lewis blood group that for years has been proposed as a useful marker for epithelial type gastrointestinal cancers. It is well known that moderately increased concentrations of CA 19-9 can be found in 15–36% of patients with benign conditions such as pancreatic, liver, biliary diseases and benign hydronephrosis. In current study, we aimed to investigate whether there was any tendency CA 19-9 e...

Introduction: Acromegaly is a chronical and rare disease which is accompanied by excessive growth hormone (GH) secreting hypohysis tumor. In this study we presented acromegaly patients’ datas who admitted to our center between the years 1998–2016. We discussed patients’ charecteristics and we aimed to investigate the determinants which is effecting the remission rate of the patients’.Method: 70 acromegaly patients datas were analyzed ...

Introduction: Metabolic syndrome (MetS) is correlated with increased cardiovascular risk and characterized by several factors, including visceral obesity, hypertension, dyslipidemia, and insulin resistance. Several members of a large family of nonselective cation channels, e.g., transient receptor potential (TRP) channels, have been associated with the development of cardiovascular diseases. Thus, changes of TRP channel expression may account for the observed increased cardiov...

Introduction: Metabolic syndrome (MetS) is characterised by a combination of visceral obesity, hypertension, insulin resistance, dyslipidemia, and impaired glucose tolerance. It is a prominent risk factor for cardiovascular morbidity and mortality. The etiology of MetS is complex. The progression of MetS is influenced by genetic susceptibility and environmental factors. The aim of this study was to investigate a possible association between transient receptor potential (TRP) c...

Introduction: In this study, we aimed to evaluate radioiodine (RAI) treatment efficacy in geriatric patients with hyperthyroidism.Design: Patients older than 65 years who received RAI treatment were included via retrospective data analyses. Eighty-two patients with hyperthyroidism (average age: 69.9 years, age range: 64–81 years) who received RAI treatment and then followed up for at least 6 months were included in the study. Patients’ clinical...

Introduction: Autoimmune thyroid diseases result from a dysregulation of the immune system leading to an immune attack on the thyroid. Autoimmune thyroid diseases, which include Graves’ disease (GD) and Hashimoto’s thyroiditis (HT), are characterised by lymphocytic infiltration of the thyroid parenchyma. The mechanisms that trigger the autoimmune attack to the thyroid are not entirely known. The aim of this study was to investigate the possible contribution of Rho/Rh...